Located at the center of Kashgar Old City, the mosque is considered one of the local landmarks.
Kashgar was historically important for its position on the ancient Silk Road, officials said.
"The mosque can accommodate around 20,000 people during the two major religious celebrations," Imam of the mosque, Mohammad Jummah, told a visiting Bangladesh media delegation.
Muslims gather at the mosque each Friday for Jummah prayers, apart from the five regular prayers each day, he said.
Residents of Kashgar enjoy better life with the growing presence of religious tourists that boost their business, officials said.
The Imam of the mosque trashed the claim that China's Xinjiang Uygur Autonomous Region has "concentration camps," calling it baseless.
"We don't believe there are any kind of concentration camps. This is just a lie," Imam Mohammad Jummah said, adding that there was an ulterior motive behind such baseless claims and propaganda.
He also said, "I am 53 years old. I have never seen any accident or violence in my life."
Claims of ‘concentration camps’ in China's Xinjiang baseless: Imam of largest mosque in region tells Bangladesh media delegation
Consuls general of 14 countries, stationed in different cities across China, visited the regional capital city of Urumqi, as well as Kashgar, Turpan and other locations in Xinjiang to experience first-hand the social and economic development of the region.
They said that Xinjiang's achievements are remarkable, and that people of all ethnic groups live in harmony and happiness, according to Xinhua.
The envoys also visited the old city of Kashgar and observed the tourism boom.
The media delegation members are Daily Jugantor Chief Reporter Masud Karim, The Business Standard Deputy Editor Titu Das Gupta, The Financial Express Special Correspondent Mir Mostafizur Rahaman, The Daily Star Diplomatic Correspondent Porimol Palma, UNB Special Correspondent AKM Moinuddin, Independent TV Special Correspondent Nafiza Dawla, ATN News Chief Reporter Ashiqur Rahman Apu, Daily Samokal Diplomatic Correspondent Tasnim Mohsin Mishu, Jamuna TV Senior Reporter Ahmed Reza and Somoy TV Diplomatic Correspondent Tajwar Mahmid.